Feature Summary Citrus Bioflavonoids plus Hesperidin is derived from citrus fruit peels, which is an abundant source of bioflavonoids. Although hesperidin is part of the bioflavonoid complex, it is so important that extra amounts are added to ensure high levels.
Bioflavonoids are brightly-coloured substances that are found in fruits and vegetables, and are typically a companion to vitamin C. Bioflavonoids are essential for the proper absorption of vitamin C and have been shown to have antioxidant properties, increase capillary strength and keep collagen healthy.
Strengthens capillaries and regulates their permeability
Reduces inflammation
Enhances immune system
Essential for proper absorption and use of vitamin C
Work as antioxidants by keeping vitamin C from being oxidized
Contraindications
Bioflavonoids are virtually non-toxic, so drug interactions are virtually unknown; however, citrus bioflavonoids contain grapefruit flavonoids that may interact with certain medications.
The reason that grapefruit is problematic with certain drugs is that it contains high levels of a flavonoid (plant pigment) called naringin.
This substance reduces the activity of a group of P450 enzymes known as CYP3A enzymes.
These enzymes are the ones your body uses to break down certain drugs, such as calcium channel blockers (used in the treatment of high blood pressure), sedatives (for example, midazolam), cyclosporin (an immune suppressant given to people who have received organ transplants) and statins (lipid-lowering drugs).
If the drugs are not metabolized, they remain in the body in higher concentrations. This increases the risk of unwanted toxic effects.
Recommended Adult Dosage 1-3 capsules daily or as directed by a health care practitioner. Keep out of the reach of children.