Ultimate Iron Complex from Enzymatic Therapy, Inc. features liquid liver fractions, a rich
source of heme iron. Heme iron is the most easily absorbed form of iron, and doesn’t cause
side effects such as nausea. Ultimate Iron Complex also includes other synergistic factors
known to increase absorption and promote healthy red blood cells.
• Ultimate Iron Complex provides highly absorbable iron with liquid liver fractions.
• Heme iron is up to 33% more absorbable in the body than non-heme iron. In fact,
non-heme forms can have as low as 2% absorbability.
• Contains the same benefi ts of heme iron found in liver, with substantially
• Signifi cantly reduced gastric side effects compared to non-heme iron supplements.
• Provides enhanced energy and endurance.
HOW IT WORKS
Ultimate Iron Complex provides essential iron and other synergistic
ingredients to help build red blood cells and maintain muscles
and nerves. Important for energy and stamina, Ultimate Iron
Complex combines liquid liver fractions, a source of heme iron,
with vitamin C, folic acid, vitamin B12, and trace minerals in a
natural form that supports the liver.
Each softgel contains:
Medicinal Ingredient Amount
Liquid Liver Fractions (Predigested Soluble Concentrate)...............250 mg
Folate (Folic Acid)...........................................................................200 mcg
Vitamin B-12 (Cyanocobalamin).....................................................100 mcg
Vitamin C (Ascorbic Acid)...................................................................60 mg
Iron (Ferrous Succinate)......................................................................25 mg
Soybean oil, gelatin capsule (gelatin, glycerin, chlorophyll), yellow
beeswax, lecithin, water.
Adults take 1 softgel daily with food. Take a few hours before or after
taking other medications.
Warning: KEEP OUT OF REACH OF CHILDREN AS THERE IS
SUFFICIENT IRON IN THIS PACKAGE TO SERIOUSLY HARM A CHILD.
Iron is essential to life. Critical to the entire process of respiration, iron
helps form hemoglobin in red blood cells and is used to transport oxygen
to cells throughout the body.1 Iron is vital to the production of many
substances in the body used for energy production, including myoglobin,
L carnitine, and aconitase. Several proteins in mitochondria contain iron,
while many enzymes depend on iron as an important cofactor.2
There are two forms of iron: heme and non-heme. Heme iron comes
from animal sources, such as beef, fish, and poultry. Plants are the main
source of non-heme iron; other sources include iron-fortified foods such
as cereal and bread. Ultimate Iron provides heme iron from the liver
fractions, ferrous succinate as non-heme iron, plus proven absorption
enhancers to provide a well-rounded, effective iron supplement.1
Research shows that non-heme iron’s absorption is significantly improved
when taken in conjunction with heme iron.3
Iron deficiency is a worldwide problem, with as much as 80 percent
of the world’s population being iron deficient.1 In the United States,
women of childbearing age are most likely to be iron deficient because of
monthly blood loss due to menstruation. In fact, 3–5 percent of women
aged 18 to 44 have iron deficiency anemia, with as many as 13 percent
having iron deficiency without anemia.4 Some researchers estimate that
up to 25 percent of American adolescent girls are iron deficient.2 Mild iron
deficiency symptoms include weakness, pale skin, irritability, and fatigue.5,6
Iron is a significant nutrient for energy and stamina, which affects
physical work performance, immunity, thermoregulation, and cognitive
functioning.6,7 Because iron is an important part of mitochondrial
enzymes, it is essential to cellular energy production.6
One randomized, placebo-controlled trial conducted on women who
went to the doctor because of occasional fatigue showed that those
who were given iron supplements experienced significant improvement
in energy versus those given placebo.8 Iron supplementation improved
energy even in women who were not shown to be deficient.6
Liquid Liver Fraction
Animal liver is rich in iron, vitamin B12, vitamin A, folate and other
vitamins and minerals; however, liver is also very high in cholesterol.9,10
Because liver extract contains heme iron, it enhances the absorption of
the iron in Ultimate Iron. Heme iron is also easier to digest and less likely
to cause stomach upset.11
The liver fractions in Ultimate Iron are supplied from cows raised in
Argentina. The cattle feed is free from additives, hormones, solvents, and
pesticides.12 Produced by exposing the liver material to enzymes that
hydrolyze the protein bonds, liquid liver extract provides the benefits of
liver without the cholesterol.11
Vitamin C, or ascorbic acid, is a powerful antioxidant that is crucial for
collagen production and immune system support. This water-soluble
vitamin also aids in iron absorption, transport, and storage.1,13 In one
study, adding ascorbic acid to a meal of rice (which provides non-heme
iron) increased iron absorption five fold.3 Adequate levels of vitamin C are
also necessary to maintain energy and strength.13
Folic acid or folate is essential to cell production and maintenance,
including blood cells. Required for support of neural tube development in
fetuses, folic acid is especially important to women of child-bearing age.14
Vitamin B12 is a water-soluble vitamin that is used by the body to produce
DNA, blood cells, and maintain healthy nerve cells. Because of its use
in the body, vitamin B12 is important to energy production.15 It also has
implications in cardiovascular health. Absorption of vitamin B12 can
diminish with age or when the stomach acid production is low.16
Chlorophyll, responsible for sustaining the life of plants through
photosynthesis, is also rich in enzymes and magnesium. Sometimes
called “plant blood,” chlorophyll is chemically similar to hemoglobin in
human blood. Foods rich in chlorophyll have been linked with increasing
hemoglobin content.17 In addition, chlorophyll has been extensively
researched for its support of the immune system.18,19
The energizing ingredients included in Ultimate Iron Complex help fight
occasional fatigue while providing the body with essential nutrients
for healthy blood and cell maintenance. Easily absorbable Ultimate
Iron Complex combines non-heme iron with heme iron from liquid liver
extracts that nourishes while being more gentle on the stomach than
other iron supplements.
Information provided by Enzymatic Therapy.
1. Dietary Supplement Fact Sheet: Iron. Office of Dietary Supplements. http://ods.od.nih.gov/factsheets/iron
asp. Accessed on May 24, 2007.
2. Fleming T., ed. Iron. In: PDR® for Nutritional Supplements. Montvale, NJ: Medical Economics Company;
3. Cook JD, Finch CA. Iron nutrition. West J Med. 1975 Jun;122(6):474-81.
4. Brutsaert TD, Hernandez-Cordero S, Rivera J, Viola T, Hughes G, Haas JD. Iron supplementation improves
progressive fatigue resistance during dynamic knee extensor exercise in iron-depleted, nonanemic women.
Am J Clin Nutr. 2003 Feb;77(2):441-8.
5. Killip S, Bennett JM, Chambers MD. Iron deficiency anemia. Am Fam Physician. 2007 Mar 1;75(5):671-8.
6. Patterson AJ, Brown WJ, Roberts DC. Dietary and supplement treatment of iron deficiency results in
improvements in general health and fatigue in Australian women of childbearing age. J Am Coll Nutr. 2001
7. Ghosh K. Non haematological effects of iron deficiency—a perspective. Indian J Med Sci. 2006 Jan;60(1):30-7.
8. Verdon F, Burnand B, Stubi CL, Bonard C, Graff M, Michaud A, Bischoff T, de Vevey M, Studer JP, Herzig L,
Chapuis C, Tissot J, Pécoud A, Favrat B. Iron supplementation for unexplained fatigue in non-anaemic
women: double blind randomised placebo controlled trial. BMJ. 2003 May 24;326(7399):1124.
9. Nutritional summary for beef, variety meats and by products, liver, raw. Nutrition Data.
http://www.nutritiondata.com/facts-C00001-01c20tw.html. Accessed on May 25, 2007.
10. Scheid HE, Schweigert BS. Vitamin B12 content of organ meats. J Nutr. 1954 Jul 10;53(3):419-27.
11. Murray, M. Glandular Extracts: What You Must Know. Keats Publishing, New Canaan, CT. 1994:22-25.
12. Farr, J. Enzymatic Therapy® Quality Assurance Department. In-house communication (electronic mail).
May 31, 2007.
13. Fleming T., ed. Vitamin C. In: PDR® for Nutritional Supplements. Montvale, NJ: Medical Economics
Company; 2001: 486-498.
14. Fleming T., ed. Folate. In: PDR® for Nutritional Supplements. Montvale, NJ: Medical Economics Company;
15. Fleming T., ed. Vitamin B12. In: PDR® for Nutritional Supplements. Montvale, NJ: Medical Economics
Company; 2001: 477-486.
16. Oh R, Brown DL. Vitamin B12 deficiency. Am Fam Physician. 2003 Mar 1;67(5):979-86.
17. Bhat, S.R. Chlorophyll: The wonder pigment. Science Reporter. 2005:42(7):29-32.
18. Kumar SS, Shankar B, Sainis KB. Effect of chlorophyllin against oxidative stress in splenic lymphocytes
in vitro and in vivo. Biochim Biophys Acta. 2004;1672(2):100-11.
19. Chiu LC, Kong CK, Ooi VE. Antiproliferative effect of chlorophyllin derived from a traditional Chinese
medicine Bombyx mori excreta on human breast cancer MCF-7 cells. Int J Oncol. 2003;23(3):729-35.
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