AOR Ortho Glucose IIDISCUSSION: Ortho Glucose II is AOR`s most advanced glucose metabolism support formula. Micronutrients at the forefront of glucose metabolism technology have been included in this formulation, which was designed to maximize insulin sensitivity and to protect against the inefficient metabolism of glucose associated with such metabolic disorders as Syndrome X and Type II Diabetes. 90 Vegi-Caps 895mg 100% Vegetarian SUPPLEMENT FACTS: Serving Size: 3 Capsules Chromium (trivalent Cr picolinate) ... 600mcg Cinnamon Extract ... 100mg Gymnemma sylvestre Extract ... 533mg Bitter Melon Extract (Momordica charantia ... 300mg Corosolic acid ... 500mcg R(+)-Lipoic Acid ... 300mg Non-medicinal ingredients: none. Capsule: hypromellose, water. AOR guarantees that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, soy, eggs, dairy, fish or shellfish. Suggested Use Take 1 capsule three times daily, half an hour before a meal, or as directed by a qualified health care practitioner. Main Applications * Increases insulin sensitivity * Supports normal blood sugar balance Source Multi-Sourced Pregnancy / Nursing No Studies, best to avoid. Cautions Persons using insulin and other diabetic medications should only use this supplement under physician supervision. FAQs Q: I Have Heard That Sorbitol Can Be Potentially Dangerous To Diabetics. Is This True? A: No. The root of the question is not entirely without merit, however, since sorbitol is structurally a sugar alcohol. However, any problem posed by excess cellular sorbitol for diabetics is that it is actually caused by excess glucose in the cell (which is converted to sorbitol in the body), and this pertains to ENDOGENOUS sorbitol. When EXOGENOUS sorbitol is introduced from capsules, the liver converts this sorbitol into glucose, leading some to believe that this can have negative metabolic implications. However, much of this sorbitol (up to 75%) is converted to CO2 and is released as perspiration. Furthermore, the amount of sorbitol found in a typical capsule is approximately 8-14 mg, and even if the conversion to glucose was complete, this would lead to an increase of blood glucose levels of 300 mcg/dl. To put that number into proper perspective, normal fasting glucose levels are 140 mg/dl, and normal non-fasting levels are approximately 400 mg/dl. These numbers represent approximately one-466th and one- 1333rd respectively the difference the amount of sorbitol in a capsule could possibly make, a negligible number brought into even clearer perspective given the fact that most glucometers are accurate to within 10-15%. Adcock LH, Gray CH. The metabolism of sorbitol in the human subject. Biochem J. 1957 Mar;65(3):554-560. Q: What is Sorbitol and Why Is It Used In AORs Capsules? A: Sorbitol, also known as glucitol, is a highly ubiquitous and naturally-occurring substance found in everything from the biochemistry of the human body to apples to chewing gum. The latter of course contains the synthetic version, and in the supplement industry sorbitol is used in capsules, tablets and softgels. Its most common roles are that of a plasticizer (to reduce capsule brittleness and enhance stability) and as a humectant (to reduce long-term leakage). Sorbitol is one of the most effective and widely used substances in the world for these and other similar purposes, spanning the food, pharmaceutical, and natural supplement industries. It holds GRAS (Generally Recognized As Safe) status with the FDA in the United States and in Canada is listed on the Ministry of Health`s list of Acceptable Non-medicinal Ingredients with a composition allowance of 90%, one of the highest of any non-medicinal ingredients. However, as of March of 2009, the capsules of AOR products will no longer contain sorbitol as a constituent.
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