AOR Vitamin D3 is derived from sheepskin oil collected during shearing. It is rapidly converted in the body to the active hormone 1,25 dihydrocholecalciferol. Adequate 1,25 (OH) D is responsible for proper function of bone growth and metabolism, and muscle function. Studies show large sections of the population in the northern latitudes are vitamin D deficient. SUPPLEMENT FACTS: Serving Size: 1 Capsule %DRI ____________________________________________________ Vitamin D3 ............................ 5000 IU 835% ____________________________________________________ *Dietary Reference Intake not established. Other ingredients: microcrystalline cellulose. Capsule: vegetarian (hydroxypropylmethylcellulose, sorbitol, silicon dioxide, water, lecithin). AOR guarantees that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish or shellfish.
Suggested Use Take one capsule per day with food, or as directed by a qualified health practitioner. Main Applications * Calcium absorption * Bone health * Auto Immune Disorders * Immune support * Normal cellular growth and differentiation Pregnancy / Nursing No studies, best to avoid. Cautions None known. The term vitamin as applied to vitamin D is inaccurate because it is synthesized by the skin following exposure to sunlight. Synthesis is dependent upon numerous factors including the type of ultraviolet and intensity, duration of exposure, skin pigmentation, age, altitude, latitude, hour of day and time of season. Vitamin D deficiency is widespread across all population groups. Most physicians recognize that the elderly population is at risk, however it is less appreciated that children, young adults and middle age groups are also at risk. Studies have shown that children in Madrid, Spain to Maine, New York were approximately 50% deficit in vitamin D in the winter months. Apart form equilateral regions where people make sufficient vitamin D, everywhere else particularly latitudes of 40N and 40S people make little vitamin D. In Edmonton which is 52N, vitamin D synthesis is impaired from October through to March. This problem is further accentuated by misinformation and inappropriate statements of avoiding sun and overuse of sunscreen by public health services. No doubt sun over exposure is associated strongly with skin cancer but too little vitamin D synthesis also has its own unique health problems. UVB exposure to the skin epidermis, produces vitamin D which then undergoes hydroxylation (addition of OH or hydroxyl group) first in the liver and then in the kidneys to produce the active hormone 1, 25-dihydroxy vitamin D. 1, 25(OH) D is responsible for not only the bone development and growth in children and maintenance of bone in adults, but also for the prevention of osteoporosis and fractures in the elderly. Vitamin D deficiency in children results in rickets and osteomalacia in adults, both conditions characterised by inadequate bone mineralization. Vitamin D is essential for the efficient utilization of dietary calcium. Blood calcium levels are tightly regulated. In a vitamin D deficit state, the amount of calcium absorbed is inadequate to satisfy the body`s requirement, this causes the body to release a hormone PTH (parathyroid hormone) which activates the cells (osteoclasts) to breakdown the bone to get the much needed calcium. This results in osteopenia and osteoporosis. Additionally, PTH causes the kidneys to excrete phosphate and the overall net result is a decrease in calcium phosphate, the major mineral required for mineralizing bone. The bone building cells-osteoblasts continue to deposit collagen matrix which results in rubbery matrix which expands upon hydration and causes pressure and a low grade unrelenting pain often misdiagnosed as fibromyalgia. Vitamin D is also important in the function of muscles. Muscle weakness, pain and changes in gait have been described in vitamin D insufficiency. This may be the reason that the elderly have more falls and consequently increased fracture rates. Vitamin D has been associated with increased hypertension, increased auto-immune diseases and various forms of cancer including breast, prostate and ironically skin. Low Vitamin D is associated with premenstrual syndrome (PMS), poor immune system, diabetes and the so called syndrome X and seasonally affective disorders. To read more about how vitamin D can help prevent flu click here. To read a Life Extension magazine article about a new study on Vitamin D - click here.
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