AOR Ortho Glucose. Ortho-Glucose is AOR’s most advanced glucose metabolism support formula, including a range of standardized botanicals along with trivalent chromium picolinate. Research has supported the ability of these nutrients to potentiate and/or mimic the glucose metabolic functions of insulin, and to activate peroxisome proliferator-activated receptors alpha and gamma –transcription factors which act as cellular lipid sensors and regulators of lipid metabolism.90 Capsules 368 mg AOR04105 _____________________________________________________________ SUPPLEMENT FACTS: Serving Size: 1 Capsule _____________________________________________________________________ Hops Isohumulones (from 100 mg Humulus lupulus L. extract)† ............. 79 mg Cinnamon (Cinnamomum zeylanicum extract)† ................................... 50 mg Corosolic acid (from 1% Lagerstroemia speciosa extract)† ............... 500 mcg Chromium (trivalent Cr picolinate)‡ .............................................. 600 mcg _____________________________________________________________________ † Natural ‡ Pharmaceutical Synthesis *Dietary Reference Intake not established. Other ingredients: Capsule: vegetarian (hypromellose, sorbitol, silicon dioxide, water, lecithin). AOR guarantees that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish or shellfish.
Suggested Use for AOR Ortho Glucose Take 1 capsule three times daily, half an hour before a meal, or as directed by a qualified health practitioner. Pregnancy / Nursing Not known, best to avoid. Cautions Persons using insulin and other diabetic medications should only use this supplement under physician supervision. Several well-researched nutrients have demonstrated that they can encourage healthy glucose metabolism. Ortho-Glucose is a nutritional formula that contains nutrients capable of supporting the action of insulin and that encourage healthy glucose metabolism: Isohumolones Extracted from hops, these bitter compounds were added to AOR Ortho-Glucose because they improve insulin sensitivity in patients with type 2 diabetes and in animals suffering from insulin resistance. Isohumulones are capable of activating peroxisome proliferator-activated receptors, which are cellular receptors with a central role in energy metabolism. These receptors regulate both the action of insulin and the metabolism of fat. They are the ideal nutrient to prevent the development and advancement of type 2 diabetes and reduce the likeliness of cardiovascular complications. Animal studies have shown that supplementation with isohumulones reduces blood triglyceride and free fatty acid levels, normalizes blood glucose levels and leads to weight loss. In type 2 diabetic patients, 8-week supplementation with isohumulones resulted in significant reductions of 6.4% in hemoglobin A1c levels and an impressive 10.1% reduction in blood glucose levels. Systolic blood pressure was also reduced by 7.2%. Cinnamon Cinnamon is a popular spice that has been known since antiquity. It is no coincidence that cinnamon is often used for the preparation of desserts. Indeed, laboratory work has demonstrated that cinnamon enhances cellular glucose uptake and utilization. Animal studies have also confirmed that supplementation with cinnamon improves the action of insulin, increases insulin levels and prevents the development of insulin resistance in animals fed a diet high in sugar. Clinical trials have revealed that the bark of this small tree is a great choice for patients suffering from type 2 diabetes mellitus. Cinnamon improves the cellular uptake of glucose through its insulin-like activity. Reported reduction of fasting plasma glucose levels varied from 10 to 29% depending on the initial glucose levels, and patients with poorly controlled blood glucose levels benefited even more from supplementation with cinnamon. As previously mentioned, diabetic patients often have abnormal blood lipid and cholesterol levels, which predisposes them to cardiac complications. After 40 days of cinnamon supplementation, blood triglycerides and cholesterol levels were significantly reduced. Cinnamon can therefore be used to avoid type 2 diabetes, decrease blood glucose levels in diabetics and reduce the risks of common complications associated with diabetes. Corosolic Acid Extracted from banana, corosolic acid delays starch digestion, has insulin-like activity and improves glucose uptake - hence its inclusion in AOR Ortho-Glucose. Animal studies showed that corosolic acid improves glucose metabolism and reduces insulin resistance. Corosolic acid given prior to an oral glucose tolerance test (a test designed to measure the body’s ability to use glucose) to subjects having various degrees of impaired glucose metabolism revealed that corosolic acid increases insulin release and reduces blood glucose levels. Chromium
Chromium is an essential mineral for the metabolism of carbohydrates. Chromium increases the sensitivity of insulin receptors, which increases the cellular transport of glucose and reduces blood sugar levels. Double-blinded, placebo-controlled studies have demonstrated that chromium supplementation lowers blood glucose levels, reduces hemoglobin A1c concentrations, and improves cholesterol levels. It has been established that lifestyle changes, dietary modifications and supplementation with nutrients capable of improving glucose metabolism are effective methods to prevent insulin resistance and manage elevated blood glucose levels. AOR Ortho-Glucose contains isohumulones, cinnamon extract, corosolic acid and chromium picolinate. These nutrients and plant extracts are supported by clinical research in diabetic subjects. They have been shown to reduce elevations in blood sugar levels, potentiate the action of insulin, improve the cellular utilization of glucose and reduce risk factors for complications associated with diabetes. They are the ideal choice for those trying to regain normal carbohydrate metabolism and striving to achieve normal blood glucose levels.
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